Hi The time of the End means the end of human nature in opposition to God and the will of God.
2 Thessalonians 1:5-10
5 This is only one example of the fair, just way God does things, for he is using your sufferings to make you ready for his Kingdom, 6 while at the same time he is preparing judgment and punishment for those who are hurting you.
7 And so I would say to you who are suffering, God will give you rest along with us when the Lord Jesus appears suddenly from heaven in flaming fire with his mighty angels, 8 bringing judgment on those who do not wish to know God and who refuse to accept his plan to save them through our Lord Jesus Christ. 9 They will be punished in everlasting hell, forever separated from the Lord, never to see the glory of his power 10 when he comes to receive praise and admiration because of all he has done for his people, his saints. And you will be among those praising him because you have believed what we told you about him.